Wednesday, January 4, 2023

COVID vaccine study raises questions about boosters | Sandusky Register Vaccines save lives, but multiple boosters for COVID may not help, study suggests

SANDUSKY — It turns out that COVID-19, and the efforts to fight it, still have some mysteries for scientists to puzzle over.

A new Cleveland Clinic study of vaccinations of thousands of its employees had a surprising finding: Employees with a high number of vaccine doses, including boosters, were more likely to contract COVID-19.

"The study found that the longer it has been since last exposure to the virus by infection or vaccination, the higher the risk of acquiring COVID-19. It also found that the higher the number of vaccine doses an individual previously received, the higher the risk of contracting COVID-19," according to a statement from the Cleveland Clinic summarizing the study.

The clinic said officials don't know what to make of the fact that the more-immunized employees also caught COVID-19 more often.

"It is unclear, at this time, why this was observed and how it should be interpreted, and more research is needed to either confirm or refute this finding. It's important to note that this paper has not yet been peer-reviewed," the statement said.

The study does not contradict massive evidence showing that the COVID-19 vaccination campaign saved many lives in the U.S. and abroad.

Vaccines remain "very effective" against severe disease and death, the study cites. And even critics of the U.S. Food and Drug Administration's fast decision to approve the newest COVID-19 booster agree that COVID vaccinations saved many lives.


Could it be that multiple vaccinations cause people to be less careful?  

There is other evidence that the bivalent vaccine is very effective at preventing disease...


When compared with unvaccinated persons, VE of a bivalent booster dose received ≥7 days before illness onset (median = 29 days) against COVID-19–associated hospitalization was 84%. Compared with persons who received ≥2 monovalent-only mRNA vaccine doses, relative VE of a bivalent booster dose was 73%. These early findings show that a bivalent booster dose provided strong protection against COVID-19–associated hospitalization in older adults and additional protection among persons with previous monovalent-only mRNA vaccination. All eligible persons, especially adults aged ≥65 years, should receive a bivalent booster dose to maximize protection against COVID-19 hospitalization this winter season. https://www.cdc.gov/mmwr/volumes/71/wr/mm715152e2.htm?s_cid=mm715152e2_w

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